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ONTOLOGY REPORT - ANNOTATIONS

Term:Leydig cell differentiation
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Accession:GO:0033327 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.

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Leydig cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amh anti-Mullerian hormone involved_in ISO (MGI:1195636|PMID:9435237) UniProt PMID:9435237 MGI:1195636 NCBI chrNW_004624828:6,635,192...6,638,104
Ensembl chrNW_004624828:6,631,420...6,637,732 		JBrowse link
G Ar androgen receptor acts_upstream_of_or_within ISO (PMID:19574395) MGI PMID:19574395 NCBI chrNW_004624891:3,135,824...3,330,487
Ensembl chrNW_004624891:3,138,848...3,329,459 		JBrowse link
G Ccnd1 cyclin D1 ISO RGD PMID:17303663 RGD:2289137 NCBI chrNW_004624767:17,470,310...17,483,082
Ensembl chrNW_004624767:17,469,622...17,483,191 		JBrowse link
G Dhh desert hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17495005)
(PMID:12050120)		 Ensembl
MGI		 PMID:12050120 PMID:17495005 GO_REF:0000107 NCBI chrNW_004624816:3,096,137...3,100,882
Ensembl chrNW_004624816:3,095,849...3,104,228 		JBrowse link
G Hsd17b10 hydroxysteroid 17-beta dehydrogenase 10 ISO RGD PMID:12810569 RGD:2302236 NCBI chrNW_004624909:681,731...684,130
Ensembl chrNW_004624909:681,731...684,237 		JBrowse link
G Hsd17b3 hydroxysteroid 17-beta dehydrogenase 3 ISO RGD PMID:18502897 RGD:4781870 NCBI chrNW_004624753:17,770,326...17,832,560
Ensembl chrNW_004624753:17,789,789...17,832,747 		JBrowse link
G LOC101704598 cholesterol side-chain cleavage enzyme, mitochondrial ISO RGD PMID:18502897 RGD:4781870 NCBI chrNW_004624781:288,594...298,876
Ensembl chrNW_004624781:288,594...300,429 		JBrowse link
G LOC101726496 steroid 17-alpha-hydroxylase/17,20 lyase ISO RGD PMID:18502897 RGD:4781870 NCBI chrNW_004624831:2,155,851...2,166,621
Ensembl chrNW_004624831:2,157,048...2,166,539 		JBrowse link
G Map7 microtubule associated protein 7 acts_upstream_of_or_within ISO (PMID:10837026) MGI PMID:10837026 NCBI chrNW_004624886:1,194,440...1,359,644
Ensembl chrNW_004624886:1,216,878...1,360,123 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 ISO RGD PMID:15149725 RGD:2302287 NCBI chrNW_004624752:21,722,593...21,737,826
Ensembl chrNW_004624752:21,720,012...21,737,809 		JBrowse link
G Nkx2-1 NK2 homeobox 1 acts_upstream_of_or_within ISO (PMID:12399445) MGI PMID:12399445 NCBI chrNW_004624838:300,902...304,944
Ensembl chrNW_004624838:300,458...305,517 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0 group B member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15829514)
(PMID:11564714)		 Ensembl
MGI		 PMID:11564714 PMID:15829514 GO_REF:0000107 NCBI chrNW_004624762:25,759,976...25,769,543
Ensembl chrNW_004624762:25,764,452...25,769,487 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5 group A member 1 acts_upstream_of_or_within ISO (PMID:15829514) MGI PMID:15829514 NCBI chrNW_004624760:10,603,504...10,626,259
Ensembl chrNW_004624760:10,605,877...10,626,386 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19056881) Ensembl
MGI		 PMID:19056881 GO_REF:0000107 NCBI chrNW_004624761:15,223,789...15,269,685
Ensembl chrNW_004624761:15,225,356...15,269,810 		JBrowse link
G Plekha1 pleckstrin homology domain containing A1 acts_upstream_of_or_within ISO (PMID:19056881) MGI PMID:19056881 NCBI chrNW_004624737:24,299,199...24,365,459 JBrowse link
G Sf1 splicing factor 1 acts_upstream_of_or_within ISO (PMID:17495005) MGI PMID:17495005 NCBI chrNW_004624767:21,606,059...21,621,831
Ensembl chrNW_004624767:21,606,065...21,621,830 		JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 acts_upstream_of_or_within ISO (PMID:19056881) MGI PMID:19056881 NCBI chrNW_004624754:4,844,472...4,889,006
Ensembl chrNW_004624754:4,844,552...4,886,709 		JBrowse link
G Tmf1 TATA element modulatory factor 1 acts_upstream_of_or_within ISO (PMID:23000399) MGI PMID:23000399 NCBI chrNW_004624773:3,587,753...3,618,089 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    reproductive process 1560
      developmental process involved in reproduction 1061
        Leydig cell differentiation 18
Path 2
Term Annotations click to browse term
  biological_process 15093
    developmental process 6156
      anatomical structure development 5795
        multicellular organism development 4711
          system development 4117
            reproductive system development 396
              reproductive structure development 391
                gonad development 301
                  male gonad development 185
                    Leydig cell differentiation 18
paths to the root